Niveau de confinement 3 (NC3)

La plateforme Niveau de confinement 3 a contribué à la publication des articles scientifiques ci-dessous.

2023

^{Chen Y, Prévost J, Ullah I, Romero H, Lisi V, Tolbert WD, Grover JR, Ding S, Gong SY, Beaudoin-Bussières G, Gasser R, Benlarbi M, Vézina D, Anand SP, Chatterjee D, Goyette G, Grunst MW, Yang Z, Bo Y, Zhou F, Béland K, Bai X, Zeher AR, Huang RK, Nguyen DN, Sherburn R, Wu D, Piszczek G, Paré B, Matthies D, Xia D, Richard J, Kumar P, Mothes W, Côté M, Uchil PD, Lavallée VP, Smith MA, Pazgier M, Haddad E, Finzi A. Molecular basis for antiviral activity of two pediatric neutralizing antibodies targeting SARS-CoV-2 Spike RBD. iScience. 2023 Jan 20;26(1):105783. doi: 10.1016/j.isci.2022.105783. Epub 2022 Dec 9. PMID: 36514310; PMCID: PMC9733284.}

^{Nicolas A, Sannier G, Dubé M, Nayrac M, Tauzin A, Painter MM, Goel RR, Laporte M, Gendron-Lepage G, Medjahed H, Williams JC, Brassard N, Niessl J, Gokool L, Morrisseau C, Arlotto P, Tremblay C, Martel-Laferrière V, Finzi A, Greenplate AR, Wherry EJ, Kaufmann DE. An extended SARS-CoV-2 mRNA vaccine prime-boost interval enhances B cell immunity with limited impact on T cells. iScience. 2023 Jan 20;26(1):105904. doi: 10.1016/j.isci.2022.105904. Epub 2022 Dec 29. PMID: 36594081; PMCID: PMC9797215.}

2022

^{Aranguren M, Doyon-Laliberté K, El-Far M, Chartrand-Lefebvre C, Routy JP, Barril JG, Trottier B, Tremblay C, Durand M, Poudrier J, Roger M; Canadian HIV and Aging Cohort Study. Subclinical Atherosclerosis Is Associated with Discrepancies in BAFF and APRIL Levels and Altered Breg Potential of Precursor-like Marginal Zone B-Cells in Long-Term HIV Treated Individuals. Vaccines (Basel). 2022 Dec 30;11(1):81. doi: 10.3390/vaccines11010081. PMID: 36679926; PMCID: PMC9863280.}

^{Beaudoin-Bussières G, Chen Y, Ullah I, Prévost J, Tolbert WD, Symmes K, Ding S, Benlarbi M, Gong SY, Tauzin A, Gasser R, Chatterjee D, Vézina D, Goyette G, Richard J, Zhou F, Stamatatos L, McGuire AT, Charest H, Roger M, Pozharski E, Kumar P, Mothes W, Uchil PD, Pazgier M, Finzi A. A Fc-enhanced NTD-binding non-neutralizing antibody delays virus spread and synergizes with a nAb to protect mice from lethal SARS-CoV-2 infection. Cell Rep. 2022 Feb 15;38(7):110368. doi: 10.1016/j.celrep.2022.110368. Epub 2022 Jan 25. PMID: 35123652; PMCID: PMC8786652.}

^{Boutin M, Vézina D, Ding S, Prévost J, Laumaea A, Marchitto L, Anand SP, Medjahed H, Gendron-Lepage G, Bourassa C, Goyette G, Clark A, Richard J, Finzi A. Temsavir Treatment of HIV-1-Infected Cells Decreases Envelope Glycoprotein Recognition by Broadly Neutralizing Antibodies. mBio. 2022 Jun 28;13(3):e0057722. doi: 10.1128/mbio.00577-22. Epub 2022 Apr 27. PMID: 35475646; PMCID: PMC9239219.}

^{Chatterjee D, Tauzin A, Laumaea A, Gong SY, Bo Y, Guilbault A, Goyette G, Bourassa C, Gendron-Lepage G, Medjahed H, Richard J, Moreira S, Côté M, Finzi A. Antigenicity of the Mu (B.1.621) and A.2.5 SARS-CoV-2 Spikes. Viruses. 2022 Jan 14;14(1):144. doi: 10.3390/v14010144. PMID: 35062348; PMCID: PMC8780535.}

^{Chatterjee D, Tauzin A, Marchitto L, Gong SY, Boutin M, Bourassa C, Beaudoin-Bussières G, Bo Y, Ding S, Laumaea A, Vézina D, Perreault J, Gokool L, Morrisseau C, Arlotto P, Fournier É, Guilbault A, Delisle B, Levade I, Goyette G, Gendron-Lepage G, Medjahed H, De Serres G, Tremblay C, Martel-Laferrière V, Kaufmann DE, Bazin R, Prévost J, Moreira S, Richard J, Côté M, Finzi A. SARS-CoV-2 Omicron Spike recognition by plasma from individuals receiving BNT162b2 mRNA vaccination with a 16-week interval between doses. Cell Rep. 2022 Mar 1;38(9):110429. doi: 10.1016/j.celrep.2022.110429. Epub 2022 Feb 8. PMID: 35216664; PMCID: PMC8823958.}

^{Ding S, Ullah I, Gong SY, Grover JR, Mohammadi M, Chen Y, Vézina D, Beaudoin-Bussières G, Verma VT, Goyette G, Gaudette F, Richard J, Yang D, Smith AB 3rd, Pazgier M, Côté M, Abrams C, Kumar P, Mothes W, Uchil PD, Finzi A, Baron C. VE607 stabilizes SARS-CoV-2 Spike in the "RBD-up" conformation and inhibits viral entry. iScience. 2022 Jul 15;25(7):104528. doi: 10.1016/j.isci.2022.104528. Epub 2022 Jun 3. PMID: 35677392; PMCID: PMC9164512.}

^{Gong SY, Ding S, Benlarbi M, Chen Y, Vézina D, Marchitto L, Beaudoin-Bussières G, Goyette G, Bourassa C, Bo Y, Medjahed H, Levade I, Pazgier M, Côté M, Richard J, Prévost J, Finzi A. Temperature Influences the Interaction between SARS-CoV-2 Spike from Omicron Subvariants and Human ACE2. Viruses. 2022 Sep 30;14(10):2178. doi: 10.3390/v14102178. PMID: 36298733; PMCID: PMC9607596.}

^{Laumaea AE, Lewin A, Chatterjee D, Marchitto L, Ding S, Gendron-Lepage G, Goyette G, Allard MÈ, Simard C, Tremblay T, Perreault J, Duerr R, Finzi A, Bazin R. COVID-19 vaccine humoral response in frequent platelet donors with plateletpheresis-associated lymphopenia. Transfusion. 2022 Sep;62(9):1779-1790. doi: 10.1111/trf.17037. Epub 2022 Aug 2. PMID: 35919021; PMCID: PMC9539235.}

^{Li W, Chen Y, Prévost J, Ullah I, Lu M, Gong SY, Tauzin A, Gasser R, Vézina D, Anand SP, Goyette G, Chaterjee D, Ding S, Tolbert WD, Grunst MW, Bo Y, Zhang S, Richard J, Zhou F, Huang RK, Esser L, Zeher A, Côté M, Kumar P, Sodroski J, Xia D, Uchil PD, Pazgier M, Finzi A, Mothes W. Structural basis and mode of action for two broadly neutralizing antibodies against SARS-CoV-2 emerging variants of concern. Cell Rep. 2022 Jan 11;38(2):110210. doi: 10.1016/j.celrep.2021.110210. Epub 2021 Dec 15. PMID: 34971573; PMCID: PMC8673750.}

^{Nayrac M, Dubé M, Sannier G, Nicolas A, Marchitto L, Tastet O, Tauzin A, Brassard N, Lima-Barbosa R, Beaudoin-Bussières G, Vézina D, Gong SY, Benlarbi M, Gasser R, Laumaea A, Prévost J, Bourassa C, Gendron-Lepage G, Medjahed H, Goyette G, Ortega-Delgado GG, Laporte M, Niessl J, Gokool L, Morrisseau C, Arlotto P, Richard J, Bélair J, Prat A, Tremblay C, Martel-Laferrière V, Finzi A, Kaufmann DE. Temporal associations of B and T cell immunity with robust vaccine responsiveness in a 16-week interval BNT162b2 regimen. Cell Rep. 2022 Jun 28;39(13):111013. doi: 10.1016/j.celrep.2022.111013. Epub 2022 Jun 13. PMID: 35732172; PMCID: PMC9189142.}

^{Prévost J, Richard J, Gasser R, Medjahed H, Kirchhoff F, Hahn BH, Kappes JC, Ochsenbauer C, Duerr R, Finzi A. Detection of the HIV-1 Accessory Proteins Nef and Vpu by Flow Cytometry Represents a New Tool to Study Their Functional Interplay within a Single Infected CD4+ T Cell. J Virol. 2022 Mar 23;96(6):e0192921. doi: 10.1128/jvi.01929-21. Epub 2022 Jan 26. PMID: 35080425; PMCID: PMC8941894.}

^{Prévost J, Anand SP, Rajashekar JK, Zhu L, Richard J, Goyette G, Medjahed H, Gendron-Lepage G, Chen HC, Chen Y, Horwitz JA, Grunst MW, Zolla-Pazner S, Haynes BF, Burton DR, Flavell RA, Kirchhoff F, Hahn BH, Smith AB 3rd, Pazgier M, Nussenzweig MC, Kumar P, Finzi A. HIV-1 Vpu restricts Fc-mediated effector functions in vivo. Cell Rep. 2022 Nov 8;41(6):111624. doi: 10.1016/j.celrep.2022.111624. PMID: 36351384; PMCID: PMC9703018.}

^{Ratnapriya S, Braun AR, Cervera Benet H, Carlson D, Ding S, Paulson CN, Mishra N, Sachs JN, Aldrich CC, Finzi A, Herschhorn A. Broad Tricyclic Ring Inhibitors Block SARS-CoV-2 Spike Function Required for Viral Entry. ACS Infect Dis. 2022 Oct 14;8(10):2045-2058. doi: 10.1021/acsinfecdis.1c00658. Epub 2022 Sep 26. PMID: 36153947; PMCID: PMC9528568.}

^{Tauzin A, Gong SY, Chatterjee D, Ding S, Painter MM, Goel RR, Beaudoin-Bussières G, Marchitto L, Boutin M, Laumaea A, Okeny J, Gendron-Lepage G, Bourassa C, Medjahed H, Goyette G, Williams JC, Bo Y, Gokool L, Morrisseau C, Arlotto P, Bazin R, Fafard J, Tremblay C, Kaufmann DE, De Serres G, Richard J, Côté M, Duerr R, Martel-Laferrière V, Greenplate AR, Wherry EJ, Finzi A. A boost with SARS-CoV-2 BNT162b2 mRNA vaccine elicits strong humoral responses independently of the interval between the first two doses. Cell Rep. 2022 Oct 25;41(4):111554. doi: 10.1016/j.celrep.2022.111554. Epub 2022 Oct 5. PMID: 36244343; PMCID: PMC9533674.}

^{Tauzin A, Gendron-Lepage G, Nayrac M, Anand SP, Bourassa C, Medjahed H, Goyette G, Dubé M, Bazin R, Kaufmann DE, Finzi A. Evolution of Anti-RBD IgG Avidity following SARS-CoV-2 Infection. Viruses. 2022 Mar 4;14(3):532. doi: 10.3390/v14030532. PMID: 35336940; PMCID: PMC8949389.}

2021

^{Anand SP, Prévost J, Nayrac M, Beaudoin-Bussières G, Benlarbi M, Gasser R, Brassard N, Laumaea A, Gong SY, Bourassa C, Brunet-Ratnasingham E, Medjahed H, Gendron-Lepage G, Goyette G, Gokool L, Morrisseau C, Bégin P, Martel-Laferrière V, Tremblay C, Richard J, Bazin R, Duerr R, Kaufmann DE, Finzi A. Longitudinal analysis of humoral immunity against SARS-CoV-2 Spike in convalescent individuals up to 8 months post-symptom onset. Cell Rep Med. 2021 Jun 15;2(6):100290. doi: 10.1016/j.xcrm.2021.100290. Epub 2021 May 5. PMID: 33969322; PMCID: PMC8097665.}

^{Bunet R, Nayrac M, Ramani H, Sylla M, Durand M, Chartrand-Lefebvre C, Routy JP, Landay AL, Gauchat JF, Chomont N, Ancuta P, Kaufmann DE, Bernard N, Tremblay CL, El-Far M. Loss of CD96 Expression as a Marker of HIV-Specific CD8+ T-Cell Differentiation and Dysfunction. Front Immunol. 2021 May 27;12:673061. doi: 10.3389/fimmu.2021.673061. PMID: 34122431; PMCID: PMC8190400.}

^{Cattin A, Wacleche VS, Fonseca Do Rosario N, Marchand LR, Dias J, Gosselin A, Cohen EA, Estaquier J, Chomont N, Routy JP, Ancuta P. RALDH Activity Induced by Bacterial/Fungal Pathogens in CD16+ Monocyte-Derived Dendritic Cells Boosts HIV Infection and Outgrowth in CD4+ T Cells. J Immunol. 2021 Jun 1;206(11):2638-2651. doi: 10.4049/jimmunol.2001436. Epub 2021 May 24. PMID: 34031148.}

^{Ding S, Adam D, Beaudoin-Bussières G, Tauzin A, Gong SY, Gasser R, Laumaea A, Anand SP, Privé A, Bourassa C, Medjahed H, Prévost J, Charest H, Richard J, Brochiero E, Finzi A. SARS-CoV-2 Spike Expression at the Surface of Infected Primary Human Airway Epithelial Cells. Viruses. 2021 Dec 21;14(1):5. doi: 10.3390/v14010005. PMID: 35062211; PMCID: PMC8778294.}

^{El-Far M, Durand M, Turcotte I, Larouche-Anctil E, Sylla M, Zaidan S, Chartrand-Lefebvre C, Bunet R, Ramani H, Sadouni M, Boldeanu I, Chamberland A, Lesage S, Baril JG, Trottier B, Thomas R, Gonzalez E, Filali-Mouhim A, Goulet JP, Martinson JA, Kassaye S, Karim R, Kizer JR, French AL, Gange SJ, Ancuta P, Routy JP, Hanna DB, Kaplan RC, Chomont N, Landay AL, Tremblay CL. Upregulated IL-32 Expression And Reduced Gut Short Chain Fatty Acid Caproic Acid in People Living With HIV With Subclinical Atherosclerosis. Front Immunol. 2021 Apr 15;12:664371. doi: 10.3389/fimmu.2021.664371. PMID: 33936102; PMCID: PMC8083984.}

^{Moreira Gabriel E, Wiche Salinas TR, Gosselin A, Larouche-Anctil E, Durand M, Landay AL, El-Far M, Tremblay CL, Routy JP, Ancuta P. Overt IL-32 isoform expression at intestinal level during HIV-1 infection is negatively regulated by IL-17A. AIDS. 2021 Oct 1;35(12):1881-1894. doi: 10.1097/QAD.0000000000002972. PMID: 34101628; PMCID: PMC8416712.}

^{Papenburg J, Cheng MP, Corsini R, Caya C, Mendoza E, Manguiat K, Lindsay LR, Wood H, Drebot MA, Dibernardo A, Zaharatos G, Bazin R, Gasser R, Benlarbi M, Gendron-Lepage G, Beaudoin-Bussières G, Prévost J, Finzi A, Ndao M, Yansouni CP. Evaluation of a Commercial Culture-Free Neutralization Antibody Detection Kit for Severe Acute Respiratory Syndrome-Related Coronavirus-2 and Comparison With an Antireceptor-Binding Domain Enzyme-Linked Immunosorbent Assay. Open Forum Infect Dis. 2021 Apr 30;8(6):ofab220. doi: 10.1093/ofid/ofab220. PMID: 34136587; PMCID: PMC8135688.}

^{Prévost J, Medjahed H, Vézina D, Chen HC, Hahn BH, Smith AB 3rd, Finzi A. HIV-1 Envelope Glycoproteins Proteolytic Cleavage Protects Infected Cells from ADCC Mediated by Plasma from Infected Individuals. Viruses. 2021 Nov 6;13(11):2236. doi: 10.3390/v13112236. PMID: 34835042; PMCID: PMC8625184.}

^{Rajashekar JK, Richard J, Beloor J, Prévost J, Anand SP, Beaudoin-Bussières G, Shan L, Herndler-Brandstetter D, Gendron-Lepage G, Medjahed H, Bourassa C, Gaudette F, Ullah I, Symmes K, Peric A, Lindemuth E, Bibollet-Ruche F, Park J, Chen HC, Kaufmann DE, Hahn BH, Sodroski J, Pazgier M, Flavell RA, Smith AB 3rd, Finzi A, Kumar P. Modulating HIV-1 envelope glycoprotein conformation to decrease the HIV-1 reservoir. Cell Host Microbe. 2021 Jun 9;29(6):904-916.e6. doi: 10.1016/j.chom.2021.04.014. Epub 2021 May 20. PMID: 34019804; PMCID: PMC8214472.}

^{Richard J, Nguyen DN, Tolbert WD, Gasser R, Ding S, Vézina D, Yu Gong S, Prévost J, Gendron-Lepage G, Medjahed H, Gottumukkala S, Finzi A, Pazgier M. Across Functional Boundaries: Making Nonneutralizing Antibodies To Neutralize HIV-1 and Mediate Fc-Mediated Effector Killing of Infected Cells. mBio. 2021 Oct 26;12(5):e0140521. doi: 10.1128/mBio.01405-21. Epub 2021 Sep 28. PMID: 34579568; PMCID: PMC8546553.}

^{Tauzin A, Nayrac M, Benlarbi M, Gong SY, Gasser R, Beaudoin-Bussières G, Brassard N, Laumaea A, Vézina D, Prévost J, Anand SP, Bourassa C, Gendron-Lepage G, Medjahed H, Goyette G, Niessl J, Tastet O, Gokool L, Morrisseau C, Arlotto P, Stamatatos L, McGuire AT, Larochelle C, Uchil P, Lu M, Mothes W, De Serres G, Moreira S, Roger M, Richard J, Martel-Laferrière V, Duerr R, Tremblay C, Kaufmann DE, Finzi A. A single dose of the SARS-CoV-2 vaccine BNT162b2 elicits Fc-mediated antibody effector functions and T cell responses. Cell Host Microbe. 2021 Jul 14;29(7):1137-1150.e6. doi: 10.1016/j.chom.2021.06.001. Epub 2021 Jun 4. PMID: 34133950; PMCID: PMC8175625.}

^{Wiche Salinas TR, Gosselin A, Raymond Marchand L, Moreira Gabriel E, Tastet O, Goulet JP, Zhang Y, Vlad D, Touil H, Routy JP, Bego MG, El-Far M, Chomont N, Landay AL, Cohen ÉA, Tremblay C, Ancuta P. IL-17A reprograms intestinal epithelial cells to facilitate HIV-1 replication and outgrowth in CD4+ T cells. iScience. 2021 Oct 7;24(11):103225. doi: 10.1016/j.isci.2021.103225. PMID: 34712922; PMCID: PMC8531570.}

2020

^{Beaudoin-Bussières G, Laumaea A, Anand SP, Prévost J, Gasser R, Goyette G, Medjahed H, Perreault J, Tremblay T, Lewin A, Gokool L, Morrisseau C, Bégin P, Tremblay C, Martel-Laferrière V, Kaufmann DE, Richard J, Bazin R, Finzi A. Decline of Humoral Responses against SARS-CoV-2 Spike in Convalescent Individuals. mBio. 2020 Oct 16;11(5):e02590-20. doi: 10.1128/mBio.02590-20. PMID: 33067385; PMCID: PMC7569150.}

^{Gantner P, Pagliuzza A, Pardons M, Ramgopal M, Routy JP, Fromentin R, Chomont N. Single-cell TCR sequencing reveals phenotypically diverse clonally expanded cells harboring inducible HIV proviruses during ART. Nat Commun. 2020 Aug 14;11(1):4089. doi: 10.1038/s41467-020-17898-8. PMID: 32796830; PMCID: PMC7427996.}

^{Niessl J, Baxter AE, Mendoza P, Jankovic M, Cohen YZ, Butler AL, Lu CL, Dubé M, Shimeliovich I, Gruell H, Klein F, Caskey M, Nussenzweig MC, Kaufmann DE. Combination anti-HIV-1 antibody therapy is associated with increased virus-specific T cell immunity. Nat Med. 2020 Feb;26(2):222-227. doi: 10.1038/s41591-019-0747-1. Epub 2020 Feb 3. PMID: 32015556; PMCID: PMC7018622.}

^{Niessl J, Baxter AE, Morou A, Brunet-Ratnasingham E, Sannier G, Gendron-Lepage G, Richard J, Delgado GG, Brassard N, Turcotte I, Fromentin R, Bernard NF, Chomont N, Routy JP, Dubé M, Finzi A, Kaufmann DE. Persistent expansion and Th1-like skewing of HIV-specific circulating T follicular helper cells during antiretroviral therapy. EBioMedicine. 2020 Apr;54:102727. doi: 10.1016/j.ebiom.2020.102727. Epub 2020 Apr 5. PMID: 32268275; PMCID: PMC7136607.}

^{Prévost J, Gasser R, Beaudoin-Bussières G, Richard J, Duerr R, Laumaea A, Anand SP, Goyette G, Benlarbi M, Ding S, Medjahed H, Lewin A, Perreault J, Tremblay T, Gendron-Lepage G, Gauthier N, Carrier M, Marcoux D, Piché A, Lavoie M, Benoit A, Loungnarath V, Brochu G, Haddad E, Stacey HD, Miller MS, Desforges M, Talbot PJ, Maule GTG, Côté M, Therrien C, Serhir B, Bazin R, Roger M, Finzi A. Cross-Sectional Evaluation of Humoral Responses against SARS-CoV-2 Spike. Cell Rep Med. 2020 Oct 20;1(7):100126. doi: 10.1016/j.xcrm.2020.100126. Epub 2020 Sep 30. PMID: 33015650; PMCID: PMC7524645.}

^{Prévost J, Edgar CR, Richard J, Trothen SM, Jacob RA, Mumby MJ, Pickering S, Dubé M, Kaufmann DE, Kirchhoff F, Neil SJD, Finzi A, Dikeakos JD. HIV-1 Vpu Downregulates Tim-3 from the Surface of Infected CD4+ T Cells. J Virol. 2020 Mar 17;94(7):e01999-19. doi: 10.1128/JVI.01999-19. PMID: 31941771; PMCID: PMC7081912.}

^{Prévost J, Tolbert WD, Medjahed H, Sherburn RT, Madani N, Zoubchenok D, Gendron-Lepage G, Gaffney AE, Grenier MC, Kirk S, Vergara N, Han C, Mann BT, Chénine AL, Ahmed A, Chaiken I, Kirchhoff F, Hahn BH, Haim H, Abrams CF, Smith AB 3rd, Sodroski J, Pazgier M, Finzi A. The HIV-1 Env gp120 Inner Domain Shapes the Phe43 Cavity and the CD4 Binding Site. mBio. 2020 May 26;11(3):e00280-20. doi: 10.1128/mBio.00280-20. PMID: 32457241; PMCID: PMC7251204.}

2019

^{Ding S, Grenier MC, Tolbert WD, Vézina D, Sherburn R, Richard J, Prévost J, Chapleau JP, Gendron-Lepage G, Medjahed H, Abrams C, Sodroski J, Pazgier M, Smith AB 3rd, Finzi A. A New Family of Small-Molecule CD4-Mimetic Compounds Contacts Highly Conserved Aspartic Acid 368 of HIV-1 gp120 and Mediates Antibody-Dependent Cellular Cytotoxicity. J Virol. 2019 Nov 26;93(24):e01325-19. doi: 10.1128/JVI.01325-19. PMID: 31554684; PMCID: PMC6880173.}

^{Fromentin R, DaFonseca S, Costiniuk CT, El-Far M, Procopio FA, Hecht FM, Hoh R, Deeks SG, Hazuda DJ, Lewin SR, Routy JP, Sékaly RP, Chomont N. PD-1 blockade potentiates HIV latency reversal ex vivo in CD4+ T cells from ART-suppressed individuals. Nat Commun. 2019 Feb 18;10(1):814. doi: 10.1038/s41467-019-08798-7. PMID: 30778080; PMCID: PMC6379401.}

^{Grenier MC, Ding S, Vézina D, Chapleau JP, Tolbert WD, Sherburn R, Schön A, Somisetti S, Abrams CF, Pazgier M, Finzi A, Smith AB 3rd. Optimization of Small Molecules That Sensitize HIV-1 Infected Cells to Antibody-Dependent Cellular Cytotoxicity. ACS Med Chem Lett. 2019 Nov 15;11(3):371-378. doi: 10.1021/acsmedchemlett.9b00445. PMID: 32184972; PMCID: PMC7074219.}

^{Pardons M, Baxter AE, Massanella M, Pagliuzza A, Fromentin R, Dufour C, Leyre L, Routy JP, Kaufmann DE, Chomont N. Single-cell characterization and quantification of translation-competent viral reservoirs in treated and untreated HIV infection. PLoS Pathog. 2019 Feb 27;15(2):e1007619. doi: 10.1371/journal.ppat.1007619. PMID: 30811499; PMCID: PMC6411230.}

^{Zaidan SM, Leyre L, Bunet R, Larouche-Anctil E, Turcotte I, Sylla M, Chamberland A, Chartrand-Lefebvre C, Ancuta P, Routy JP, Baril JG, Trottier B, MacPherson P, Trottier S, Harris M, Walmsley S, Conway B, Wong A, Thomas R, Kaplan RC, Landay AL, Durand M, Chomont N, Tremblay CL, El-Far M; Canadian HIV and Aging Cohort Study. Upregulation of IL-32 Isoforms in Virologically Suppressed HIV-Infected Individuals: Potential Role in Persistent Inflammation and Transcription From Stable HIV-1 Reservoirs. J Acquir Immune Defic Syndr. 2019 Dec 15;82(5):503-513. doi: 10.1097/QAI.0000000000002185. PMID: 31714430; PMCID: PMC6857723.}

2018

^{Porichis F, Hart MG, Massa A, Everett HL, Morou A, Richard J, Brassard N, Veillette M, Hassan M, Ly NL, Routy JP, Freeman GJ, Dubé M, Finzi A, Kaufmann DE. Immune Checkpoint Blockade Restores HIV-Specific CD4 T Cell Help for NK Cells. J Immunol. 2018 Aug 1;201(3):971-981. doi: 10.4049/jimmunol.1701551. Epub 2018 Jun 22. PMID: 29934472; PMCID: PMC6064609.}

2017

^{Baxter AE, Niessl J, Fromentin R, Richard J, Porichis F, Massanella M, Brassard N, Alsahafi N, Routy JP, Finzi A, Chomont N, Kaufmann DE. Multiparametric characterization of rare HIV-infected cells using an RNA-flow FISH technique. Nat Protoc. 2017 Oct;12(10):2029-2049. doi: 10.1038/nprot.2017.079. Epub 2017 Sep 7. PMID: 28880280; PMCID: PMC5697908.}

^{Reiss S, Baxter AE, Cirelli KM, Dan JM, Morou A, Daigneault A, Brassard N, Silvestri G, Routy JP, Havenar-Daughton C, Crotty S, Kaufmann DE. Comparative analysis of activation induced marker (AIM) assays for sensitive identification of antigen-specific CD4 T cells. PLoS One. 2017 Oct 24;12(10):e0186998. doi: 10.1371/journal.pone.0186998. PMID: 29065175; PMCID: PMC5655442.}

2016

^{El-Far M, Kouassi P, Sylla M, Zhang Y, Fouda A, Fabre T, Goulet JP, van Grevenynghe J, Lee T, Singer J, Harris M, Baril JG, Trottier B, Ancuta P, Routy JP, Bernard N, Tremblay CL; Investigators of the Canadian HIV+ Slow Progressor Cohort. Proinflammatory isoforms of IL-32 as novel and robust biomarkers for control failure in HIV-infected slow progressors. Sci Rep. 2016 Mar 15;6:22902. doi: 10.1038/srep22902. PMID: 26978598; PMCID: PMC4792165.}