Description

The laboratory of Marc Prentki is searching for highly motivated and talented post-doctoral candidates to work on the biochemistry, cell biology and translational applications of a novel metabolic enzyme that has recently been discovered in our laboratory: glycerol 3-phosphate phosphatase (G3PP). It controls glucose, lipid and energy metabolism and acts as a nutrient excess detoxification machine. Our recent work indicates that this enzyme is also implicated in aging and healthspan. We wish to assess its role in metabolic dysfunction-associated fatty liver disease, as well as senescence and healthy aging. This will be achieved using mouse models with nutritional excess or diabetes and studies in various organs and at the whole body level via changes in G3PP expression or pharmacological modulation.

The position offers an extraordinary team-based science environment located in the heart of Montreal Canada. The CRCHUM is a world renowned basic and clinical research center, the largest in QC, with multidisciplinary researchers from all over the world and many dedicated technological platforms. The selected candidate(s) will enjoy opportunities for exciting biomedical research, technological developments, education, and career development on translational projects.

Qualifications
•    Ph.D. obtained in the last 4 years in biochemistry, biology, physiology, pharmacology or a related field.
•    Highly motivated and able to work independently and in a team setting.
•    Critical thinking and communication skills.
•    Expertise in cell culture, basic biochemical and molecular biology techniques, rodent studies, animal handling, genotyping and colony management.
•    Prior experience in the preparation and handling of rodent hepatocytes is desirable.
•    Good knowledge of English; knowledge of French is an asset.
•    A track record of first author publications in peer-reviewed and well-recognized scientific journals.

Competitives benefits
•    Full-time position, 35 hours per week, daytime from Monday to Friday
•    The salary will be that recommended by the Institution and commensurate with experience. 
•    2 years contract, renewable
•    The successful candidates will be encouraged to apply for their own fellowships.
•    Start date: as soon as possible
 

To apply for this position

Interested candidates should email a letter of motivation, CV with publication list, transcripts and the contact information for 2-3 references to: marc.prentki@umontreal.ca

It is "essential" to attach your CV for your application to be considered.

Only successful candidates will be contacted for an interview.

The CRCHUM invites women, Aboriginals, visible minorities, ethnic minorities and people with disabilities to apply. The CRCHUM adopts a broad and inclusive definition of diversity that goes beyond applicable laws. 

The CRCHUM thus encourages all people, regardless of their characteristics, to apply. In accordance with Canadian immigration requirements, please note that priority will be given to Canadian citizens and permanent resident.