Genetic engineering and animal modelling
The generation and use of reliable and adequate animal models are essential tools in biomedical research.
The CRCHUM's genetic engineering and animal modelling core facility offers its academic and industrial partners several animal modelling services based in part on CRISPR-Cas9 technology, for which it received a user licence from the Broad Institute in 2017 and from ERS Genomics in 2023.
Since the establishment of this service, we have developed a deep expertise acquired through 34 projects including classical KO models, specific point mutations and conditional KOs (insertion of loxP).
The core facility’s team can also provide you with customized support and expertise tailored to the specific needs of your research projects.
We are confident that we can assist and accelerate your new projects that require animal modelling.
Our services are available to researchers from the academic, hospital and industrial sectors.
User licences
Jean-François Schmouth
PhD
Manager
Mariette Ouellet
BSc
Research Officer
Guillaume Bernas
MSc
Research Officer
Andréa Barrios
AHT
Animal Health Technician
Karine Bélanger
AHT
Animal Health Technician
Mélodie Takla
BSc
Laboratory Technician
Éric Samarut
PhD, MBA
Scientific Advisor
In numbers
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34 CRISPR projects completed since 2017 (including 3 in cells)
> 13,994 samples genotyped in 2022
> 820 rodent lines cryopreserved and stored at the CRCHUM