• Research into the understanding of the mechanisms involved in the etiology of osteoarthritis in humans and in experimental models. Using experimental models, new therapeutic strategies are investigated.
• The study of biomarkers using longitudinal and clinical research cohorts related to osteoarthritis in either serum or assessed by magnetic resonance images (knee structure). 
• The epidemiological study of determinants involved in the therapeutic responses of osteoarthritis patients using statistical models.
• Clinical studies on the effects of treatments to stop the disease; Studies on pain and joint structure using magnetic resonance imaging. 

These studies are done in both humans and experimental models.