Research on the characterization of pathways that govern maladaptive renal vascular remodeling and of the importance of these pathways in renal dysfunction in transplant and kidney disease patients. Characterization of endothelial cell death biomarkers for better prediction and prevention of renal fibrosis triggered by acute kidney injury.

Characterization of the molecular pathways controlling the biogenesis and immunogenic activities of apoptotic exosome-like vesicles (ApoExo) and anti-LG3 and translation of these findings in humans to improve prediction and management of rejection.

Marie-Josée Hébert is a nephrologist-transplanter and researcher at the Centre hospitalier de l'Université de Montréal (CHUM), a professor in the Faculty of Medicine and the Shire Chair in Nephrology and Renal Transplantation and Regeneration. She is one of the founders of the National Transplantation Research Program of Canada, which she co-directed until 2022. Her work has led to the discovery of new mechanisms involved in organ transplant rejection and chronic kidney disease.

A Fellow of the Canadian Academy of Health Sciences, she won the Dr. John B. Dossetor Award (2015) and the Medal for Research Excellence (2016) from the Kidney Foundation of Canada in recognition of her outstanding contribution to nephrology research.

Since November 2015, she has been Vice-Rector for Research, Discovery, Creation and Innovation at the University of Montreal. In this capacity, she has played a central role in the development of major cross-sectoral research and knowledge mobilization initiatives including the Institute for Data Valorization (IVADO), Mila, the Digital Health Consortium, and the Montreal Declaration for Responsible Development of Artificial Intelligence.

She was appointed Chair of the Canadian Institutes of Health Research Governing Council in September 2022.

Research funding: CIHR, Kidney Foundation of Canada, FRQS.