The research program established in our laboratory focuses on pulmonary pathologies especially cystic fibrosis, acute respiratory distress syndrome and primary graft dysfunction following lung transplantation.

Our goals are:

A) to better understand the role of ion channels in lung physiology and alveolar homeostasis

B) to identify new therapeutic targets and strategies to

1. restore the functional integrity of the respiratory airway epithelium in cystic fibrosis, by targeting the CFTR channel and bacterial infection
2. promote the resolution of acute respiratory distress syndrome parameters 
3. prevent the development of primary graft dysfunction after lung transplantation

To achieve our goals, we use state-of-the-art technologies, established animal models as well as rare human specimens, available in our Biobank of Respiratory Tissues and primary Cells.

These projects are funded by the CIHR, NSERC, the Quebec Respiratory Health research Network and the Ministry of Economy and Innovation.